Arsenal star Alexis Sanchez has been linked with a move away
Alexis [Sanchez] will not be available for example, so I can not go into the game with too many uncertainties. "Of course when you have treatment on medical bench it's not easy".
For the first time since 1997, Arsenal are going into a season without Champions League football and Wenger has pledged to rest players in the Europa League.
The latest round of rumours have linked Sanchez, who has less than 12 months to run on his current contract at Arsenal, with an £80million move to Paris Saint-Germain.
And he remains one of Arsenal's most important players, capable of turning a game on its head with a single moment of inspiration. However, the midfielder is unlikely to be rushed back to action for the game against Leicester as Wenger has enough options in midfield.
"I think he had in his career some bad moments because he had some small injuries", the manager added.
Arsenal forward Alexis Sanchez was the only player to reach double figures for both goals (24) and assists (10) in the Premier League last season.
Sanchez sustained the injury during a training session ahead of the Community Shield and Wenger admits he is unsure just how long the 28-year-old will be out.
Wenger insists he will not relent on Sanchez's future though, claiming nothing has changed from last season and that he will not be sold.
'When you are not completely in or the players feel you are not completely in, it is hard to tell them we go [out to win]. "I don't think I would have included him certainly on Friday night - I don't think I would have started him".
"Plenty of uncertainties about players who didn't play against Chelsea - Ramsey, Ozil, Mertesacker".
Arsenal's first five Premier League fixtures are against Leicester, Stoke, Liverpool, Bournemouth and Chelsea.
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