April 22, 2018

Dormant breast cancer 'can resurface 15 years later'

10 November 2017, 03:08 | Lena Norman

Nation Builders shows support for breast cancer month

Annet Sewraj and Dr Zemfundo Portia Malevo

All of the patients were given a type of anti-oestrogen therapy, such as tamoxifen or an aromatase inhibitor, for five years as part of their treatment. Numerous women in the current study began treatment as early as 1976, when there wasn't a wide range of breast cancer treatment options available.

This risk is evident even among patients with the best prognoses, say the authors.

This is because the cancer is caused by the hormone oestrogen causing cells to grow.

"Our main aim was to determine whether we could identify subgroups of women who stop endocrine therapy after five years in whom long-term risks are so small that any additional benefits from extended therapy would be unlikely to outweigh the additional side effects", write the authors in the New England Journal of Medicine.

Although the women didn't have cancer during the five-year time period, the researchers found that after they stopped taking the drugs, about 11,000 women had cancer recur at another site on their body over the next 15 years.

Veterans Day celebrated November 11
The public is invited to attend the event, which will honor all veterans and recognize Vietnam-era veterans. There are approximately 21 million living veterans in the United States.

Professor Richard Gray, one of the lead authors from the University of Oxford, said that treatment has improved since numerous women were diagnosed so recurrence rates would be somewhat lower for today's patients.

Dr Hongchao Pan, from Oxford University, said: "It is remarkable that breast cancer can remain dormant for so long and then spread many years later, with this risk remaining the same year after year". All of the participants were prescribed hormone therapy drugs for five years, a typical treatment for this type of cancer that helps to suppress tumors. However some patients choose to halt hormone treatments early because of side effects such as menopausal symptoms, osteoporosis, joint pain or carpal tunnel syndrome.

It's important to point out that since this research began, new drugs are being used to treat breast cancer, and these work in a different way to tamoxifen.

He said: "It's vital that work continues to better predict which cancers might return".

"We would urge all women who have had treatment for breast cancer not to be alarmed, but to ensure they are aware of the signs of recurrence and of metastatic breast cancer, and to speak to their GP or breast care team if they have any concerns".

Other News

Trending Now

The painting of van Gogh found fragments of a grasshopper
The remains of a grasshopper was discovered on the canvas " Olive trees ", which van Gogh painted in 1889. It was conservator Mary Schafer who first made the discovery as the museum revealed in a press release.

You can now have BREAKFAST at Tiffany's, and we're booking a flight
Follow the renovation of the fourth floor at NY flagship, Tiffany & Co will be launching its first ever retail dining concept. The Blue Box will be open 10 7 p.m., Monday through Saturday, and 12 6 p.m. on Sundays.

Apple is finally releasing a patch for that annoying iOS keyboard bug
That update is expected to include the Apple Pay Cash feature Apple revealed months ago at the Worldwide Developers Conference. Developers in the USA reportedly saw the the Apple Pay Cash option appear in the Messages app on the iOS 11 .2 beta this week.

Apple's offshore move has allegedly helped save them billions in taxes
In the new tax plan proposed by US President Donald Trump, companies would only pay 12 percent on overseas profit. The move, beginning in 2015, allowed Apple to continue to avoid paying billions of dollars in taxes.

Variants Explained In Detail — Ford EcoSport
The new edition sports an all-new three-cylinder 1.5-litre Ti-VCT petrol engine which offers fuel efficiency of 17 km per litre. The split grille of the previous EcoSport has been replaced by a smaller version of the one found on the larger Endeavour.

Opel will go profitable, electric and global, according to PSA's plans
PSA last month already announced 400 job cuts through voluntary redundancies at Vauxhall's Ellesmere Port plant in England. Combining strengths will unleash annual synergies on Groupe PSA level of €1.1 billion by 2020 and €1.7 billion by 2026.

Oil prices stabilise just below two-year highs
Energy Information Administration said it forecast domestic crude oil production in 2018 to rise by more than previously expected. US supermajor ConocoPhillips said Wednesday its three-year spending plan was supported so long as WTI held above $50 per barrel.

BTS Confirmed To Make Appearance On 'The Ellen Show'
On the other hand, the guesting comes just two days after they make their debut U.S. According to Billboard , tickets have already been sold out on ticketing site 1iota.

England's Jake Ball suffers sprained ankle ahead of the Ashes
After a second-ball duck in England's tour opener last week against a Western Australian XI in Perth, Cook faced only 28 balls. England later confirmed that Ball had suffered a sprained ankle and would miss the rest of the day's play.

Vodafone and CityFibre partner on ultrafast broadband in UK
Vodafone has announced plans to provide up to five million United Kingdom properties with "full fibre" internet connections. Openreach is already pursuing a plan to connect fibre to 10 million United Kingdom homes and businesses by the mid-2020s.